WebApr 1, 2008 · One of the mechanisms for acyclovir-induced nephrotoxicity is acyclovir-induced crystalluria. Prompt attention to urine microscopy examination can help avoid drug-induced nephrotoxicity. WebFeb 1, 1996 · In addition, crystalluria can be due to drugs such as sulphadiazine, acyclovir, triamterene, piridoxylate, primidone, which under the influence of various …
Zovirax Disease Interactions - Drugs.com
WebAcyclovir-induced crystalluria Acyclovir-induced crystalluria Ann Pharmacother. 2002 Mar;36(3):526.doi: 10.1345/aph.1A297. Authors Amy Paxton Blossom 1 , John D Cleary, William P Daley Affiliation 1School of Medicine, University of Mississippi Medical Center, Jackson 39216-4505, USA. PMID: 11895069 WebAcyclovir crystals may precipitate in the renal tubules, particularly when the drug is injected intravenously as a bolus. Abnormal renal function may occur, which is usually reversible but may infrequently progress to tubular damage and acute renal failure. dewar cryogenic cooler
Acute renal failure related to topical acyclovir - Clinical Advisor
WebJun 1, 1988 · One patient was rechallenged with low-dose intravenous acyclovir and the four patients later received oral acyclovir, all without adverse effect. The combined data from these patients support crystalluria and obstructive nephropathy as a mechanism of acyclovir-induced renal failure in humans. WebAug 1, 2024 · Aciclovir [9- (2-hydroxyethoxymethyl)guanine] is an acyclic nucleoside in the class of nucleoside analogues. 112 It is a substrate and specific inhibitor of herpesvirus DNA polymerase, blocking DNA synthesis, and is effective against herpes simplex virus type 1 and 2 and varicella-zoster virus infections, as well as several other viruses. WebAcyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. It shows good in vitro activity against herpes simplex and varicella-zoster viruses. ... The most important adverse effect is crystalluria and elevated serum creatinine related to bolus intravenous administration. Other reported adverse effects ... dewar dentist thame