WebDec 15, 2015 · While IRP ablation in DC expectedly increased basal FTH1 protein levels, it did not prevent FTH1 stimulation by LPS (Figure S4 D). Hence, LPS regulation of FTH1 in DC is largely independent of the IRP/IRE system and could reflect alternative IRP-independent regulation of FTH1 as, for instance, observed in fibrosarcoma cells ( Daba … WebSep 22, 2024 · Astrocytes were significantly decreased in AD, while oligodendrocytes and OPCs increased. Cell-to-cell ligand–receptor interaction analysis revealed that astrocytes, neurons, and OPCs mainly established contacts with other cells via the NRG3–ERBB4 ligand–receptor pair. ... FTH1 and SAT1 were identified to impact astrocyte ferroptosis ...
Efficiency of Ferritin as an MRI Reporter Gene in NPC Cells Is …
WebFerritin (FTH) is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and bioavailable form (1). The assembled ferritin molecule, often … WebMar 17, 2024 · Ferroptotic cell death has also been associated with dysfunction of the intestinal epithelium, which contributes to several intestinal diseases. ... FTL ferritin light chain, FTH1 ferritin heavy ... krups f30901 filterkaffeemaschine proaroma
Ferritinophagy in the etiopathogenic mechanism of related diseases.
WebHowever, FTH1-overexpression-related cytotoxicity is required to be explored. METHODS: By using the Tet-Off system, FTH1 overexpression was semi-quantitativiely and dynamicly regulated by doxycycline in a NPC cell line. Effects of FTH1 overexpression on the proliferation, cytotoxicity, apoptosis and migration of NPC cells were investigated in ... WebMar 21, 2024 · FTH1 (Ferritin Heavy Chain 1) is a Protein Coding gene. Diseases associated with FTH1 include Hemochromatosis, Type 5 and Macular Dystrophy, … WebFeb 2, 2024 · Iron-dependent necrotic cell death is characterized by iron overload and an increased level of lipid reactive oxygen species (ROS) such as lipid hydroperoxides, leading to phospholipid damage, plasma membrane disruption, and caspase- and necrosome-independent cell death (Dixon et al., 2012). Ferroptosis is a form of iron-dependent … krups fabrication