WebJan 1, 2008 · Because our signaling pathway likely modulates the actin cytoskeleton in spines, we used mRFP-βactin, which has been used extensively (Brunig et al., 2004; Calabrese and Halpain, 2005; Fischer et al., 2000; Star et al., 2002), to quantify changes of spine density and morphology. β and γ actin are preferentially localized in dendritic spines … WebJun 15, 2005 · The actin cytoskeleton and its anti-apoptotic regulator gelsolin are targets of caspase action during apoptosis. The destruction of these cytoskeletal components …
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WebDec 21, 2024 · The regulatory role of actin cytoskeleton on mitochondrial function is a growing research field, but the underlying molecular mechanisms remain poorly … Webthe actin cytoskeleton, presumably mediated by actin-associated proteins under the con-trol of incoming guidance signals. This article reviews how one such family of proteins, the ADF/cofilins, are emerging as key regulators of growth cone actin dynamics. These proteins are essential for rapid actin turnover in a variety of different cell types. playeras 3d
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WebMar 1, 2011 · The pathways downstream of Rho that impinge on actin are the subject of this Cell Science at a Glance article. For each cellular structure in a ‘typical’ adherent cell, we have incorporated information on the specific role of Rho effectors. Some background on these effectors, their regulation and their actin-related roles is provided in the ... WebJun 15, 2024 · structural support, the actin cytoskeleton has long been understood to play important roles in intracellular organelle and cargo move-ment. Although several studies have shown that protection of the actin cytoskeleton can beneficially impact lifespan (Higuchi et al., 2013; Baird et al., 2014), a direct characterization of actin cytoskele- WebThe dynamic regulation of the actin cytoskeleton during hypoxia is complex, varies in different cells and tissues, and also depends on the mode of hypoxia. Several molecular players and pathways are emerging that contribute to the modulation of the actin cytoskeleton and that affect the large repertoire of actin-binding proteins in hypoxia. primary hsv mouth